Element Biosciences
Element Biosciences builds high-accuracy sequencing systems on avidite base chemistry (ABC): flexible and upgradable as your throughput grows.
Dual-capable NGS sequencing and onboard multiomics platform
High-throughput benchtop platform, built for what comes next
Enter your panels, sample count and target depth, and the AVITI™ Run Planner works out flow cell allocation, the Gb and polony budgets, and cost per sample across AVITI™, AVITI24™ and AVITI LT™.
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The platforms
The AVITI™ family (AVITI LT™, AVITI™ and the multiomics-ready AVITI24™) is built on avidite base chemistry for accuracy and flexibility. As throughput grows, AVITI LT™ upgrades to AVITI™ and AVITI™ upgrades to AVITI24™.
VITARI™: shipping H2'26
A high-throughput sequencer in a compact benchtop footprint, with right-sized run configurations on two independent flow cells and run times aligned with real lab workflows.
The four platforms side by side
Output and performance for each platform, from Element Biosciences' published specifications.
Every per-run figure for AVITI™, AVITI24™ and VITARI™ assumes two flow cells running at the same time. AVITI LT™ runs one flow cell at a time, so its per-run figures are for one.
Specifications
| AVITI LT™ | AVITI™ | AVITI24™ | VITARI™ | |
|---|---|---|---|---|
| Suited to | Targeted panels and smaller batches | Exome, whole genome and somatic panels | The same, plus cytoprofiling and multiomics | High-volume whole genome sequencing |
| Upgrade | Software update to full-throughput AVITI™ | Upgrade to AVITI24™ | Not applicable | Not applicable |
| Flow cells | 1 per run | 2 independent, 2 lanes each | 2 independent, 2 lanes each | 2 independent, 6 lanes each |
| Output tiers | Low, Medium | Low, Medium, High, Cloudbreak™ UltraQ | Low, Medium, High, Cloudbreak™ UltraQ | High Output 2 x 150, the one flow cell announced (5 billion reads) |
| Read lengths | 2 x 75, 2 x 150 | 2 x 75, 2 x 150, 2 x 300 | 2 x 75, 2 x 150, 2 x 300 | 2 x 150 |
| Accuracy | >90% Q30 | >90% Q30 at 2 x 75 and 2 x 150, >85% at 2 x 300; UltraQ ≥90% Q40 and ≥70% Q50 | >90% Q30 at 2 x 75 and 2 x 150, >85% at 2 x 300; UltraQ ≥90% Q40 and ≥70% Q50 | >90% Q30 |
| Output per flow cell | Up to 150 Gb | Up to 300 Gb | Up to 450 Gb | Up to 1.5 TB |
| Output per run | Up to 150 Gb | Up to 600 Gb | Up to 900 Gb | Up to 3 TB |
| Reads per run | Up to 500 million | Up to 2 billion | Up to 3 billion | Up to 10 billion |
| Against AVITI LT™ | 1x | 4x | 6x | 20x |
The "Suited to" row is Genique's reading of the range; everything else is Element's. AVITI™ family figures are for AVITI™ OS 3.4 or later, under which AVITI24™ carries about 50% more on 2 x 75 and 2 x 150 kits. Accuracy is against Element's own libraries, so library type and preparation can move it.
Output per run, by kit (Gb, two flow cells; one on AVITI LT™)
| Kit | AVITI LT™ | AVITI™ | AVITI24™ | VITARI™ |
|---|---|---|---|---|
| Low Output 2 x 75, Freestyle only | 15 | 30 | 45 | Not available |
| Low Output 2 x 150 | 75 | 150 | 225 | Not available |
| Medium Output 2 x 75 | 75 | 150 | 225 | Not available |
| Medium Output 2 x 150 | 150 | 300 | 450 | Not available |
| Medium Output 2 x 300 | Not available | 120 | 120 | Not available |
| High Output 2 x 75 | Not available | 300 | 450 | Not available |
| High Output 2 x 150 | Not available | 600 | 900 | 3,000 |
| High Output 2 x 300 | Not available | 360 | 360 | Not available |
| Cloudbreak™ UltraQ High Output 2 x 150 | Not available | 480 | 480 | Not available |
Reads per run, by kit (millions, two flow cells; one on AVITI LT™)
| Kit | AVITI LT™ | AVITI™ | AVITI24™ | VITARI™ |
|---|---|---|---|---|
| Low Output 2 x 75, Freestyle only | 100 | 200 | 300 | Not available |
| Low Output 2 x 150 | 250 | 500 | 750 | Not available |
| Medium Output 2 x 75 | 500 | 1,000 | 1,500 | Not available |
| Medium Output 2 x 150 | 500 | 1,000 | 1,500 | Not available |
| Medium Output 2 x 300 | Not available | 200 | 200 | Not available |
| High Output 2 x 75 | Not available | 2,000 | 3,000 | Not available |
| High Output 2 x 150 | Not available | 2,000 | 3,000 | 10,000 |
| High Output 2 x 300 | Not available | 600 | 600 | Not available |
| Cloudbreak™ UltraQ High Output 2 x 150 | Not available | 1,600 | 1,600 | Not available |
Reads are Element's target read counts, one per polony, so a read pair counts once. AVITI LT™ runs Low and Medium Output at 2 x 75 and 2 x 150; High Output and 2 x 300 need the upgrade to AVITI™. Element has announced one VITARI™ flow cell so far, High Output 2 x 150, so no other VITARI™ kit is available yet.
Samples per run
| Application, data per sample | AVITI LT™ | AVITI™ | AVITI24™ | VITARI™ |
|---|---|---|---|---|
| Whole genome, 100 Gb | 1 | 6 | 8 | 30 |
| Clinical exome, 12 Gb | 12 | 50 | 74 | 250 |
| Comprehensive solid tumour panel, DNA and RNA, 12.3 Gb | 12 | 48 | 72 | 242 |
Whole samples one flow cell holds on the highest-output 2 x 150 kit, times two flow cells for AVITI™, AVITI24™ and VITARI™ and one for AVITI LT™, which is how the AVITI™ Run Planner counts them. Data per sample is the planner's own preset. Pooling, index limits and QC margins bring the real figure down; plan a run in the planner for yours.
Sources: Cloudbreak™ Sequencing User Guide, Element Biosciences MA-00058 Rev. H, for kit output and reads; Element's AVITI™ and AVITI24™ specification pages for Q30 and UltraQ; Element's published VITARI™ specification. Vendor specifications, subject to change.
Why we offer it
Q40+ accuracy, low run costs and a clear upgrade path make it a strong foundation for a modern NGS lab.
Where it sits in the Genique stack
Element Biosciences is the sequencing tier, and it is the anchor the rest of the stack is arranged around. A lab buying an AVITI™ system from Genique is buying into a chain that Genique also supplies at every other step.
- 01 · Sample prep
Extraction & reagents
- 02 · Library prep
Targeted panels & single-cell
- 03 · Sequencing
AVITI™ · AVITI24™ · VITARI™
- Element Biosciences
- 04 · Analysis
Analysis & interpretation
- 05 · Report
Interpretation & reporting
- Upstream: extraction and reagents from Seasun Biomaterials, and library preparation from Paragon Genomics, SOPHiA GENETICS, Gene Solutions, Diatech Pharmacogenetics or Atrandi Biosciences depending on the application.
- On the instrument: AVITI LT™, AVITI™ and the multiomics-ready AVITI24™, all on avidite base chemistry.
- Downstream: Sentieon or Genique bioinformatics for secondary analysis, Genomize SEQ for interpretation and reporting, and SOPHiA DDM™, which picks the run up at FASTQ and covers both steps.
- What that means in practice: one purchase order, one point of contact and one team accountable for the whole path from sample to signed-out report.
What a lab needs to run it
Site requirements for the AVITI24™ System, read off the site prep guide Element Biosciences publishes. These are manufacturer specifications rather than Genique estimates, and they are what a laboratory plans around before delivery.
- Bench and clearance: 95.5 cm wide, 72.3 cm deep, 74.9 cm high and 155 kg, on a sturdy isolated bench, with 15 cm clear at each side and behind, 92 cm in front and 48 cm above for access to the air filter.
- Power: 100 to 240 V at 50 or 60 Hz, which covers Indian mains directly, on a dedicated single-phase 15 A circuit with no extension cord. 600 W average and 1200 W peak. An uninterruptible supply rated at least 865 W or 1500 VA is recommended by the manufacturer.
- Ambient: 18 to 26 °C at 30 to 70 per cent relative humidity, non-condensing, below 2000 m, with roughly 500 W of heat to carry away in normal use.
- Kit storage: a freezer at minus 25 to minus 15 °C and a refrigerator at 2 to 8 °C, because library prep and sequencing kits ship frozen while flow cells are held chilled.
- Data: a 2 x 151 sequencing run writes about 470 GB on AVITI™ OS 3.4 or later, and a cytoprofiling run 41 to 77 GB depending on the flow cell, so the storage connection is worth sizing before installation rather than after.
- Delivery: Element delivers, unpacks and places the instrument, and a Genique field service engineer commissions it with a performance verification run.
How Genique supports it in India
Supplied, installed and supported by Genique in India as the official channel partner.
- Lead time: four weeks from purchase order to delivery.
- Service: an engineer on site, from the field team in six cities.
- Training: on site, for as many people as the laboratory needs trained rather than a fixed number of seats. One to two days.
- Consumables: four weeks to replenish.
Regulatory status in India
Element supplies sequencing instruments and the kits that run on them, and both are labelled by the manufacturer for research use.
- Labelling: Research Use Only. That holds even where a product carries CE-IVD, CE-IVDR or FDA marking in another jurisdiction, because an approval granted elsewhere does not travel to India.
- CDSCO: nothing on this page is approved or licensed by the Central Drugs Standard Control Organisation as an in-vitro diagnostic device.
- What accreditation does and does not cover: accreditation of a laboratory evidences the quality system and the method validation under which work is performed. It does not change the regulatory status of an assay.
- What this means for a NABL laboratory: the platform is the instrument the laboratory validates its own methods on, and the validation evidences the method rather than approving the assay.
See it in action
More videos (4)
Across the Element portfolio: AVITI24™ multiomics, Trinity™ and Avidity Sequencing chemistry, from loading to base calls. Videos courtesy of Element Biosciences.
Brochures
Product and solution documentation, straight from Element Biosciences.
More than a supplier. A local partner.
Local support
Field application and engineering teams across six cities in India: Gurugram, Delhi, Mumbai, Chennai, Bengaluru and Hyderabad.
Consumables continuity
Managed import, customs clearance and cold-chain logistics keep reagents flowing without interruption.
Validated onboarding
Our in-house bioinformatics team validates the platform into working pipelines, so it delivers results, not just readouts.
Interested in Element Biosciences?
Talk to our team about how it fits your needs.